The laboratory rat, like its wild counterpart, is an extremely intelligent animal, probably more so than the other rodents commonly used for biomedical research. Take a look at one such laboratory rat shopping emporium to get an idea of how researchers find and purchase their subjects. Long evans cinnamon what abnormality does this rat exhibit. This is reflected in its behaviour and, when treated properly and sympathetically, its tolerance to handling and restraint. This chapter presents the taxonomy of laboratory rat and discusses its stocks and strains. Fawn hooded rat what types of abnormalities does this rat have.
Click download or read online button to the lab rat chronicles book pdf for free now. Today, the black rat is restricted to areas near water. Both seasoned and beginning investigators will be amazed at the range and complexity of rat behavior as described in the 43 chapters of this volume. The jackson laboratory, charles river laboratories, taconic farms, and harlan laboratories are the main suppliers. With the advent of genetic manipulations and biomedical research technological advances such as bioimaging, the versatility and usefulness of the rat as an animal model has soared. Sep 09, 2012 the laboratory rat is an inevitable part of todays biomedical research. A laboratory manual of the anatomy of the rat by hunt, harrison randall, 1889publication date 1924 topics rats, anatomy. The rat estrous cycle averages four to five days in length, occurs throughout the year without seasonal influence in laboratory colonies, and occurs from pubertal onset until senescence, including during the postpartum period bennett and vickery, 1970. Dec 20, 2005 the laboratory rat, second edition features updated information on a variety of topics including. Rats are thought to have originated in the area of asia currently occupied by southern russia and northern china. Laboratory rats introduction origin and development.
Full text full text is available as a scanned copy of the original print version. Analysis of behavior in laboratory rats sciencedirect. Guidelines for the housing of rats in scientific institutions. Pdf the behavior of the laboratory rat researchgate. Whishaw, forrest haun and bryan kolb introduction to see the world in a grain of sand and a heaven in a wildflower hold infinity in the palm of your hand and eternity in an hour john donne 1 the nervous system is designed to produce behavior, and so behavioral analysis is the.
The first part of this book retraces the biomedical history of early events and personalities involved in the establishment of rats as a leading laboratory animal. How we measure reads a read is counted each time someone views a publication summary such as the. We have a pellet maker in our animal house at college. Since the tail of the rat is a major thermoregula tory organ with a large surface available for heat loss, an enhanced blood flow in the dilated veins and hence a successful venipuncture can be ensured y warming prior to injection. The quick reference section brings together all tables from the text, allowing readers to find data swiftly. A laboratory rat or lab rat is a rat of the species rattus norvegicus domestica which is bred and kept for scientific research. No pains were spared to make this a perfect and readable description of the anatomy of the laboratory rat. Luckily, lab supply has a huge selection of feeds for laboratory rats from labdiet and testdiet. Guidelines for the housing of rats in scientific institutions animal welfare branch, nsw department of primary industrie s, locked bag 21, orange nsw 2800. Pdf a quantitative trait locus influencing anxiety in. Two of the most common vertebrates used for research are mice mus musculus and rats rattus norvegicus deacon, 2006. The first volume in the handbook of experimental animals series, the laboratory rat, provides researchers in academia and industry using laboratory animals with comprehensive, practical information on the species. Whishaw and others published the behavior of the laboratory rat find, read and cite all the research you need on researchgate. The laboratory rat, second edition features updated information on a variety of topics including.
A laboratory manual of the anatomy of the rat internet archive. Sensorimotor tests are undertaken to evaluate the sensory and motor abilities of animals. While less commonly used for research than mice, rats have served as an important animal model for research in psychology and biomedical science. Request pdf the laboratory rat this second edition features updated information on a variety of topics including. Collect fecal pellet from an individual animal using brief manual restraint or by. Young rats are easier to inject into the tail vein than older ones whose tail skin is exceedingly tough and covered by scales, making it quite difficult to ierce and enter the vessels. But, the precise correlation between age of laboratory rats and human is still a subject of debate. Hepatitis fulminant hepatitis and jaundice at four months of age.
The laboratory rat handbook of experimental animals pdf free. The third edition of the laboratory rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. Laboratory anatomy of the white rat pdf slideshare. They are recognized as the preeminent model in numerous fields, including neurobehavioral studies, cancer and toxicology. Index of companies in the biotech and pharmacetuical business organized by name, state or province, and city. Baker flynns parasites of laboratory animals seco nd ed ition american college of laboratory anim. The laboratory rat handbook of experimental animals 9780124264007 by krinke, george j. Laboratory rodent diet is now available at lab supply. The behavior of the laboratory rat article pdf available january 2005.
In this booklet you will find all the information that was already present in the earlier editions. Download pdf the lab rat chronicles free online new books. This book provides important information for those working with laboratory rats. According to the preface, readers are assumed to have some knowledge of mammalian anatomy and, naturally, this would normally be so, but such knowledge is not necessary for the reader of this book. Rats are rodents, and thus members of the largest family of mammals. National academy of sciences is a private, nonprofit, selfperpetuating society of distinguished scholars engaged in scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the general welfare. The ufaw handbook on the care and management of laboratory and other research animals.
Pdf by late 18th or early 19th century, albino rats became the most commonly used experimental animals in numerous biomedical. Learn vocabulary, terms, and more with flashcards, games, and other study tools. The laboratory rat the ufaw handbook on the care and. The laboratory rat handbook of experimental animals usp. For example, the amounts of nutrients required to sustain maximum growth of young rats may be different from the. Research uses next to the laboratory mouse, the rat is the most commonly used laboratory mammal, accounting for approximately 20% of the total number of mammals. The information is provided by 50 contributors from eight countries. Rattus rattus black or ship rat, 2n 38 was well established in europe by 1100 a. Searching for the scientists equivalent to okcupid. A premier source of information on the laboratory rat that will be of interest to.
The laboratory rat american college of laboratory animal medicine veterinary laboratory medicine, an issue of clinics in laboratory medicine, 1e the clinics. The laboratory rat american college of laboratory animal. May 20, 2016 laboratory anatomy of the white rat pdf 1. Whether you are looking for irradiated diets, certified diets, or simple standard diets for your lab rats, we have exactly what you are looking for. The laboratory rat is the domesticated form of the species. The behavior of the laboratory rat a handbook with tests edited by ian q. This specialized diet is designed for rats, mice, hamsters, and gerbils that are in a laboratory or facility. Guide for the care and use of laboratory animals, 8th edition.
Revised september 2009 2 the common laboratory rat rattus norvegicus is an ideal experimental animal for several reasons. Association dangerous goods regulations manual iata. Biology and diseases focuses on the use of rats in specific areas of research, ranging from dental research to toxicology. Since the tail of the rat is a major thermoregula tory organ with a large surface available for heat loss, an enhanced blood flow in the dilated veins. Abnormal platelet function hypertension other hooded rats what is the lec rat. Introduction to the laboratory rat mcgill university. Only a few alterations have been made, especially in the text concerning decontamination and inactivation. The laboratory rat, second edition captures the multiple advances in this important animal models husbandry, veterinary care, and experimental methodology. A quantitative trait locus influencing anxiety in the laboratory rat.
The laboratory rat has long been used in experimental physiology and has made significant contributions to several complex areas of mammalian biology. Lab rat bridges the gap between the events of the video games portal and portal 2 and tells an exciting new story set in the world of aperture science. Although the nutrient requirements of the laboratory rat are better known than those of other laboratory animals, there can be considerable disparity in estimated requirements as a consequence of the criteria used baker, 1986. Read, highlight, and take notes, across web, tablet, and phone. This is the third, revised edition of the booklet biosafety in the laboratory. The common laboratory rat, rattus norvegicus, is an ideal experimental animal. Internal medicine small animal internal medicine, 5e small animal medicine small animal internal medicine small animal.
A summary and overview of the mice and rats used in biomedical research, based on a survey of formal publications. The laboratory rat handbook of experimental animals. The new edition continues the tradition of being one of the best references for laboratory animal veterinarians, graduate and postgraduate students, and researchers with interest in the biology, breeding, care, use, and diseases of the laboratory rat. This chapter presents the analysis of behavior in laboratory rats. Warming the whole rat to a temperature around 400c by placing the animal into a thermostatically warmed hotbox.
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